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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKG1
All Species:
4.55
Human Site:
S381
Identified Species:
14.29
UniProt:
Q13976
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13976
NP_001091982.1
671
76364
S381
V
E
L
V
Q
L
K
S
E
E
S
K
T
F
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851997
510
57367
D258
I
M
Q
G
A
H
S
D
F
I
V
R
L
Y
R
Cat
Felis silvestris
Mouse
Mus musculus
P0C605
671
76332
S381
V
E
L
V
Q
L
K
S
E
E
S
K
T
F
A
Rat
Rattus norvegicus
Q64595
762
87163
K473
R
V
E
L
V
K
V
K
N
E
N
I
A
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q03043
1088
121322
G798
V
E
L
V
Q
T
N
G
D
S
S
R
S
F
A
Honey Bee
Apis mellifera
NP_001011581
678
77281
G388
V
E
L
V
Q
I
A
G
D
S
S
R
S
F
A
Nematode Worm
Caenorhab. elegans
O76360
780
86723
G490
V
E
L
V
C
V
N
G
D
K
A
K
T
F
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P06245
380
44201
P128
M
L
K
L
V
E
H
P
F
L
I
R
M
W
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
68.6
N.A.
99.5
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40.9
61.2
45.1
N.A.
Protein Similarity:
100
N.A.
N.A.
72.2
N.A.
99.8
65.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
51.1
75.9
61.6
N.A.
P-Site Identity:
100
N.A.
N.A.
0
N.A.
100
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
53.3
53.3
N.A.
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
73.3
80
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
13
0
0
0
13
0
13
0
75
% A
% Cys:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
13
38
0
0
0
0
0
0
% D
% Glu:
0
63
13
0
0
13
0
0
25
38
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
25
0
0
0
0
75
0
% F
% Gly:
0
0
0
13
0
0
0
38
0
0
0
0
0
0
13
% G
% His:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% H
% Ile:
13
0
0
0
0
13
0
0
0
13
13
13
0
0
0
% I
% Lys:
0
0
13
0
0
13
25
13
0
13
0
38
0
0
0
% K
% Leu:
0
13
63
25
0
25
0
0
0
13
0
0
13
0
0
% L
% Met:
13
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% M
% Asn:
0
0
0
0
0
0
25
0
13
0
13
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% P
% Gln:
0
0
13
0
50
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
0
0
0
0
0
0
50
0
0
13
% R
% Ser:
0
0
0
0
0
0
13
25
0
25
50
0
25
0
0
% S
% Thr:
0
0
0
0
0
13
0
0
0
0
0
0
38
0
0
% T
% Val:
63
13
0
63
25
13
13
0
0
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _